ON7- New biocement from onion for dental application

Overview

The active compound was extracted from a wild species of onion. by using the combination of maceration and ultrasound. Extraction conditions were optimized by using response surface method (RSM) with a central composite design (CCD). The optimal extraction yield was 82.8 %. The antioxidant activities of the extract were evaluated from β-carotene bleaching and many others tests. Data show that the extract presents outstanding antioxidant activities. Biocompatibility of the extracts was evaluated using hemolysis and cytotoxicity assays. The adhesion force was determined by using DMA metravib machine.
All results give an important power to use it in dental application
– Strong Adhesion Force (5 MPa)
– High diffusion in dentine’s (10 μm)
– High antioxidant activity (Anti-lipophilic radicals with IC50 = 0.12mg/mL, inhibition of 98.3 % at 1mg/mL.)
– Nontoxic with Safety factor > (155)
– High thermal stability 200C